Striker Ross McCormack marked his return from a hamstring injury with the opener in their 2-0 FA Cup victory over the Royals, setting up an exciting fourth-round tie against Arsenal.
Joe Ledley, who has been heavily linked with a January move away from the Welsh capital, grabbed the second and will again line up against Nigel Clough's newly-acquired side, much to the relief of Bluebirds fans.
Midfielder Peter Whittingham also started the cup clash at Ninian Park and will be confident of keeping his place in the side.
Gabor Gyepes remains at the heart of defence alongside Roger Johnson after dislodging club captain Darren Purse, who will start from the bench.
Winger Chris Burke could make his debut for the promotion hopefuls if he completes his proposed move from Rangers in time.
Nigel Clough will be without defender Jordan Stewart for his first game in charge of the Rams.
Stewart sits out the third and final game of his suspension after his sending-off against Ipswich so Mohammed Camara will continue at left-back.
Andy Todd was given a surprise start in the 1-0 Carling Cup win over Manchester United after returning from a loan spell at League One side Northampton and could keep his place in the back four after a fine display.
Fellow defender Martin Albrechtsen is again a doubt after he jarred his knee against Forest Green in the FA Cup last weekend while Claude Davis has resumed training after his latest knee problem but will be short of fitness after almost six weeks on the sidelines.
All eyes will be on playmaker Kris Commons after his stunning winner against United as Clough looks for a promising start.