Liverpool legend Fowler, 31, is edging closer to full fitness after a thigh injury and should earn at least a place on the substitutes' bench.
Hasselbaink, meanwhile, proved he is fit and ready for action after making a goalscoring start to his Bluebirds career on Tuesday.
The former Leeds, Chelsea and Middlesbrough forward, 35, claimed a brace in Cardiff's 4-2 win at Hereford in a behind-closed-doors friendly.
Dave Jones has included the pair in his squad to face the Sky Blues, leaving former Aston Villa midfielder Ricky Scimeca (groin) as the only injury absentee.
The Bluebirds go into the game after an impressive 2-0 win against QPR at Loftus Road last weekend.
Midfielder Stephen Hughes could make his first start of the season for Coventry.
Veteran Michael Hughes is struggling with a thigh strain, so boss Iain Dowie is likely to call on the former Arsenal player.
Skipper Arjan De Zeeuw is making good progress in his recovery from medial knee ligament damage and hopes to feature for the reserves next week, with a view to facing Preston the following weekend.
Experienced central defender Robert Page is doubtful with a knock and is set to undergo a late fitness test.
Fellow defender David McNamee is ruled out with a calf injury, while Colin Hawkins is also sidelined with a groin strain.