Tom Heaton, Rob Earnshaw, Darcy Blake, Rudy Gestede and Joe Mason will all be pushing to start against the Foxes having been named on the bench for Saturday's 1-1 draw at Blackpool.
The likes of defenders Paul Quinn, Dekel Keinan and Gabor Gyepes and striker Jon Parkin will also come into the reckoning.
Deadline-day signing Ben Turner suffered a minor strain in training and will not be selected this evening.
Steve McPhail is set for his firt game of the season..
Cardiff meet Leicester for a place in the last 16 of the League Cup before welcoming the Foxes back to the Welsh capital for Sunday's Championship showdown.
Michael Johnson will make only his second Leicester appearance.
The former Manchester City midfielder has shaken off a knee injury and will be one of a number of changes made by manager Sven-Goran Eriksson following Saturday's win over Brighton.
Chris Weale, Jeffrey Schlupp, Lloyd Dyer, Steve Howard, Frank Moussa, Sean St Ledger and Neil Danns could all come into the side.
Full-back Michael Ball may also be included if he overcomes a calf problem but veteran midfielder Matt Oakley has sustained a back injury and will miss out.
Winger Paul Gallagher remains sidelined after damaging ankle ligaments against Barnsley last week and striker David Nugent is still out with a hamstring problem.