Ledley missed the last two games with a groin injury. He's joined in the squad by former City players Aaron Ramsey, Chris Gunter, James Collins and Jason Koumas.
Wales squad: Wayne Hennessey (Wolves), Boaz Myhill (Hull City), Gareth Bale (Tottenham Hotspur), James Collins (West Ham United), Neal Eardley (Oldham Athletic), Chris Gunter (Tottenham Hotspur), Craig Morgan (Peterborough United), Lewin Nyatanga (Derby County), Sam Ricketts (Hull City), Ashley Williams (Swansea City), Jack Collison (West Ham United), Simon Davies (Fulham), David Edwards (Wolves), Carl Fletcher (Crystal Palace, loan Nottingham Forest), Jason Koumas (Wigan Athletic), Joe Ledley (Cardiff City), Aaron Ramsey (Arsenal), David Vaughan (Blackpool), Craig Bellamy (West Ham United), Ched Evans (Manchester City), Sam Vokes (Wolves).