"It was a poor showing down there last time and it's fair to say we owe them (Plymouth) one," said Bothroyd. "We have to win this one today. We've built up a little fortress at Ninian Park and have to make sure that continues. Teams don't like coming to our ground here to play against us.
"Before the Reading match on Friday, we would probably have accepted a draw, but in the end we thought we should have won it.
"I've never played in a game where the goalkeeper has scored before, but I suppose it didn't matter in the end who got the goal. We let one in and we were disappointed.
"But having a home game just two days on against Plymouth gives us an opportunity to deal with that disappointment.
"We need to pick ourselves up. recover properly - and take our frustrations out on Plymouth.
"Having two matches in two days is hardly ideal, because you can't recover fully. But every club is in that situation and you just have to get on with it."
And Bothroyd is looking further ahead to Cardiff City gaining promotion. But he first had a dig at Reading after Friday's game, which should stoke the fire ahead of next Saturday's FA Cup meeting between the teams at Ninian Park.
"They've got a rubbish pitch, just hump the ball into corners and get around it. If anyone was trying to play football, it was us.
"We got a point from the match, but we sense it was more like two lost.
"When Reading played us at our ground a few weeks ago, we played them off the park. We made a couple of mistakes which let them in for two goals, but even their own manager said they were lucky to get a point against us that day.
"We meet Reading again in the FA Cup next weekend, but our eyes are very much on promotion to the Premiership.
"We want to get out of this league. What would you rather do ... win the FA Cup and still be in the Championship, or be in the Premiership and not win the FA Cup?
"We want to get out of this league, we want promotion."